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Azacitidine was administered at a
2019-04-17
Azacitidine was administered at a dose of 75mg/m2/daily subcutaneously for 7 consecutive days every 28days. Transient neutropenia was observed until the seventh cloprostenol of the azacitidine treatment was completed. A gradual increase in his blood cell count was noted and the patient eventually b
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br Sebastian Vollmer and colleagues April
2019-04-17
Sebastian Vollmer and colleagues (April, 2014) conclude that “the contribution of economic growth to the DIG-11-dUTP in early childhood undernutrition in developing countries is very small, if it exists at all”. Progress will therefore require a shift from “the so-called trickle-down approach of
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br Conclusions br Disclosures br Introduction Since their in
2019-04-17
Conclusions Disclosures Introduction Since their introduction, at the end of fifties, cardiovascular implantable devices (CIEDs) have widely expanded in number and in their functions [1,2]. The dramatic increase in the number of CIEDs implanted in the last decade is mainly due to the aging
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br Purpose br Methods Participating centers Forty main ICSD
2019-04-17
Purpose Methods Participating centers: Forty main ICSD centers in Japan from Hokkaido to Okinawa, which cover approximately 20% of all new ICSD patients in Japan, are participating in the present study. After obtaining written informed consent, all patients (over 20 years old) will be register
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br Discussion We successfully prevented the initiation
2019-04-17
Discussion We successfully prevented the initiation of AF without inhibiting the AF-triggering APB, and eliminated the AF-triggering APB located close to the sinus node without damage to sinus node function. Nifekalant is an IKr antagonist that prolongs the duration of myocardial mek inhibitors a
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alkylation of dna The lead ECG and dimensional geometrical
2019-04-17
The 12-lead ECG and 2-dimensional geometrical maps for corrected RT interval difference and corrected Tp–e interval difference obtained by using 187-ch RIDM-ECG before and during the intravenous amiodarone infusion for representative cases are shown in Figs. 1 and 2 respectively. The mean value of Q
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br Conflict of interest br Acknowledgments br Introduction
2019-04-17
Conflict of interest Acknowledgments Introduction Electroanatomical mapping is useful for locating a possible reentrant circuit, but it has limitations in terms of analyzing the functional property of the circuit [1,2]. Entrainment mapping using the postpacing interval (PPI) and the activat
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As la historia a la vez ejemplar e ilustrativa
2019-04-17
Así, la historia, a la vez ejemplar e ilustrativa, es un elemento aglutinador de la identidad del pueblo mexicano pues conforma la narración unificadora necesaria para fusionar, en una identidad única, a la sociedad mexicana. Por ello, para Vigil, la enseñanza de la historia convertiría “a los habit
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ubiquitin e3 ligase br X Desde esa exigencia de una correcta
2019-04-17
X. Desde esa exigencia de una correcta hermeneusis receptora, la mecánica expositiva del misterio procederá, sin embargo, complicando esa primera alegoría que ya es el sacramento en sí y levantando, ubiquitin e3 ligase partir de la transposición o metáfora que diseña (Cristo como pan, Cristo como
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br Material and methods br
2019-04-16
Material and methods Results Discussion Activated microglia has been shown to be a hallmark of central nervous system (CNS) inflammation, which further mediating the subsequent neuronal apoptosis [1], [2], [3], [27], [28]. However, the underlying molecular mechanisms have not been well eluc
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br Conclusion br Conflict of interest statement br Authors c
2019-04-16
Conclusion Conflict of interest statement Authors\' contribution Introduction There are two classes of bisphosphonates that differ with regard to structure and mechanism of action [1]. The first one includes pyrophosphate-resembling bisphosphonates, such as clodronate and etidronate, whi
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In this issue of Mark Nicol and colleagues
2019-04-16
In this issue of , Mark Nicol and colleagues report the diagnostic accuracy of two commercially available rapid urine tests to identify active tuberculosis in children. Lipoarabinomannan is a unique component of the mycobacterial A-366 manufacturer that is excreted in the urine of some patients wit
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HF is associated with the down regulation of multiple
2019-04-16
HF is associated with the down-regulation of multiple potassium (K) currents (i.e., Ito, IKs, IKr, IK1, and IKATP). The only K channel that is upregulated in HF is the small conductance Ca-activated K (SK) channel. The SK channel was originally found in most neurons. The increase in Cai evoked by th
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br Conflict of interest br Case presentation A year old
2019-04-16
Conflict of interest Case presentation A 64-year-old female presented to the emergency room with persistent dizziness that began early that morning. She had a 30-year history of palpitations and known electrocardiogram (ECG) abnormalities. Her pulse was irregular at 130–270min−1 and blood pres
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Extensive vascularization of the skeletal
2019-04-16
Extensive vascularization of the skeletal tissue suggests the importance of blood vessels in regulating its physiological functions. Endothelium, the innermost cellular layer of blood vessels forms a central component of the bone marrow vascular microenvironment [7]. Recent evidence support that a p
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