• br We recently reported associations between maternal

  2019-06-19

  

  We recently reported associations between maternal age at childbirth and outcomes in the offspring, using data from five birth cohorts (COHORTS collaboration) in low-income and middle-income countries (LMICs), in . Young maternal age ( Antimicrobial resistance is recognised as a serious global h

• br Acknowledgments This work was supported by grants

  2019-06-19

  

  Acknowledgments This work was supported by grants from the National Science Council (project number: MOST-103-2320-B-040-004 and NSC 102-2313-B-002 -039 -MY3). The authors would like to thank Dr. Bernard A. Schwetz for carefully reading the manuscript and helpful discussions which improved the ar

• br CaMKII and heart failure

  2019-06-19

  

  CaMKII and heart failure progression CaMKII is a multifunctional serine–threonine kinase, phosphorylating target proteins. Under resting conditions, CaMKII is inactive. A rise in intracellular Ca2+ stimulates binding of Ca2+ to calmodulin (CaM), a ubiquitous Ca2+-binding protein. The Ca2+/CaM com

• Zerumbone As for the detection rate we should select a

  2019-06-19

  

  As for the detection rate, we should select a different setting in patients with primary prevention and secondary prevention because ICD patients with primary prevention experience the faster lethal arrhythmia with an average rate of 200 beats per minute [27]. On the other hand, ICD recipients with

• br Bile acids as therapeutic agents

  2019-06-18

  

  Bile acids as therapeutic agents Conclusion Bile acids are important physiological agents for nutrient purchase Arecaidine but-2-ynyl ester tosylate and integrators of glucose, lipid, and energy metabolism control. Bile acid synthesis is tightly regulated to maintain metabolic homeostasis and

• Stroke is second only to ischaemic heart

  2019-06-18

  

  Stroke is second only to ischaemic Naltrindole hydrochloride disease as the leading cause of death worldwide; one in six people will have a stroke in their lifetime. , on October 29, reminds us of these striking facts and the need for individuals to know the risk factors. Although the main risk fac

• The increasing burden of NCDs poses an enormous threat to

  2019-06-18

  

  The increasing burden of NCDs poses an enormous threat to populations and health systems across the globe. The Sustainable Development Goals represent an important opportunity to integrate efforts to reduce the burden of NCDs and promote sustainable development. The recent identification of NCDs as

• More than million almost children younger than

  2019-06-18

  

  More than 200 million—almost 40%—children younger than 5 years in developing countries are not fulfilling their developmental potential. In parts of Africa, up to three-quarters of children are victims of physical abuse, and a third of girls and more than 10% of boys are victims of sexual abuse. One

• br Point of care diagnostic tests POCTs can enable

  2019-06-18

  

  Point-of-care diagnostic tests (POCTs) can enable health-care workers to provide more rapid and effective care to people in low-resource settings. POCTs should ideally meet the WHO\'s ASSURED criteria—ie, being affordable, sensitive, specific, user-friendly, rapid and robust, equipment-free, and d

• br Una de las m s acres y

  2019-06-18

  

  Una de las más acres y reiteradas recriminaciones CVT 10216 la tl provenientes de los sectores eclesiales más conservadores, ha estado fundada en el uso del instrumental teórico de origen marxista y su tesis de la lucha de clases, debido a que se le atribuye una irreconciliable incompatibilidad co

• Finally the effects of In

  2019-06-18

  

  Finally, the effects of 111In-NLS-CSL360 on hematopoietic function in healthy Balb/c mice was studied. Groups of 2–4 mice were injected i.v. with 6.1±1.4MBq, 18.8±1.5MBq or 35.8±0.9MBq of 111In-NLS-CSL360 or an equivalent mass (70μg) of unlabeled CSL360 or received normal saline. At two weeks post-t

• Two important issues affect our interpretation of these find

  2019-06-18

  

  Two important issues affect our interpretation of these findings. First, many women chose institutional delivery (53% of deliveries were at hospitals in Sazawal and colleagues\' trial, and 64% in Semrau and colleagues\' trial). The latest WHO guidelines recommend application of chlorhexidine to the

• Bennet and colleagues also make an important addition to the

  2019-06-18

  

  Bennet and colleagues also make an important addition to the literature on the Affordable Medicines Facility—malaria (AMFm) intervention, since a comparison of ACT treatment coverage for countries that had the AMFm intervention is made with those for countries that did not have the AMFm intervention

• Could new approaches to global

  2019-06-18

  

  Could new approaches to global nutrition lead to interventions that would make children grow tall without putting on excessive fat, as is the case for present-day piglets? Animal science has been addressing this issue for a long time, although with rigorous studies that cannot be conducted in humans

• Education is part of the foundation for a

  2019-06-18

  

  Education is part of the foundation for a successful ASP. A well-designed educational program provides prescribers with updated knowledge on antimicrobial use, drug resistance, and infectious disease management. Educational interventions have been shown to improve prescribing competency, change pre

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