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The dihydroxynaphthalene derived substrates a
2019-07-02

The 2,3-dihydroxynaphthalene-derived substrates 18a, 20a and 22a (Table 2) allowed only moderate growth of all members of the panel of microorganisms suggesting that these substrates were inhibitory to some extent. Strong growth of the Gram-negative microorganisms and moderate growth of the Gram-pos
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All known vertebrate TRIMs are categorized in distinct subcl
2019-07-02

All known vertebrate TRIMs are categorized in 11 distinct subclasses depending on the types of domains present at their carboxyl-terminals (Fig. 3) [29], [35]. Beyond conserved N-terminal domains, it is the C-terminal that provides specificity of interactions with other proteins. The subclass IV for
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Bovine collagen type II a fibrillar collagen mainly found in
2019-07-01

Bovine collagen type II, a fibrillar collagen mainly found in cartilage, comprises 24 potentially glycosylated lysine residues within its collagen domain. Detailed analysis revealed that 22 out of 23 of these lysine residues are hydroxylated and carry variable numbers of Gal(β1-O) and Glc(α1-2)Gal(β
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The increasing complexity and demands of the proper diagnosi
2019-07-01

The increasing complexity and demands of the proper diagnosis and management of patients with inherited cardiovascular disease create an opportunity for the development of specialized training for clinical electrophysiologists interested in the care of patients with inherited arrhythmias [229]. Such
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The increasing complexity and demands of the proper diagnosi
2019-07-01

The increasing complexity and demands of the proper diagnosis and management of patients with inherited cardiovascular disease create an opportunity for the development of specialized training for clinical electrophysiologists interested in the care of patients with inherited arrhythmias [229]. Such
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Diagnosis of pituitary metastasis could be
2019-07-01

Diagnosis of pituitary metastasis could be missed by medical practitioners because most patients who developed pituitary metastasis are clinically asymptomatic. Patients may have signs and symptoms of nausea, vomiting, fatigue, and weight loss, which could also be viewed as pan-hypopituitarism, and
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Introduction Bone metastases are a common manifestation
2019-07-01

Introduction Bone metastases are a common manifestation of cancer [1]. Most patients present with pain and impaired mobility, while others can develop complications such as pathological fractures and aldose reductase of the spinal cord or cauda equina [2]. Many randomized studies have been conduct
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br Discussion Compared to the right ventricular outflow
2019-07-01

Discussion Compared to the right ventricular outflow tract, the LVOT has a more complicated anatomic structure, comprising the mitral annulus, aortic cusps, and LV basal myocardium. The AMC bridges the aortic and mitral valves with fibrous tissue, called the left fibrous trigone [3], and the exte
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A type saddle back type
2019-07-01

A type 2 (“saddle-back type”) or type 3 ST-segment elevation cannot substitute for a type 1, unless converted to type 1 with fever or sodium drug challenge. A drug challenge–induced type 1 can be used to diagnose BrS only if accompanied by 1 of the criteria specified above. Type 2 is characterized b
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GPCR Compound Library NAFLD and fatty liver is the accumulat
2019-07-01

NAFLD and fatty liver is the accumulation of fat and cholesterol in hepatocytes. NAFLD is one of the most common liver diseases in the USA and worldwide. NAFLD is associated with obesity, inflammation and insulin resistance. Fat accumulation in the liver is due to the uptake and synthesis (intake) o
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El Grounded Theory permite un an
2019-07-01

El Grounded Theory permite un análisis mucho más profundo y cualitativo de estos textos constitucionales. Si además los concebimos como “narrativas constitucionales”, escritas por muchas manos (los participantes directos o indirectos de las Asambleas Constituyentes) con la pretensión de definir el s
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onde introduzimos a negritude como
2019-07-01

É onde introduzimos SEN0014196 of negritude como uma concepção adotada pelos intelectuais e movimentos sociais ligados à causa negra no Brasil. A negritude foi conceituada por seu criador, o poeta e intelectual Aimé Cesairé, como “o simples reconhecimento do fato de ser negro, a aceitação de seu des
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There has been scant prior research
2019-06-29

There has been scant prior research focusing on the clinical efficiency and safety of either BV alone or in combination with chemotherapy in treating relapsed or refractory CD30+ T cell lymphoma, ALCL and HL. Although the most common and significant adverse events of BV, such as peripheral neuropath
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br Conflict of interest br
2019-06-29

Conflict of interest Acknowledgment Introduction The majority of clot embolisms associated with atrial fibrillation (AF) are from the left atrial appendage (LAA). Before cardioversion or catheter ablation, clot formation needs to be ruled out traditionally using transesophageal echocardiogr
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VV optimization From the foregoing
2019-06-29

VV optimization From the foregoing discussion, it is clear that AV delay programming to ensure ventricular preexcitation with optimal LV diastolic filling and systolic function is complex, and the optimal method that translates into improved patient outcomes is uncertain. These issues are even mor
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